Calcium Channel Blocker Toxicity with Merritt Tuttle

Dr. Merritt Tuttle is both a Pediatric Intensivist and Medical Toxicologist at Brenner Children's Hospital in North Carolina associated with Atrium Health and Wake Forest Baptist Health. She completed her Pediatric Critical Care and Medical Toxicology training at the Medical College of Wisconsin.

Learning Objective: By the end of this podcast, listeners should be able to discuss an evidence based and expert guided approach to the evaluation and management of the critically ill child with calcium channel blocker toxicity.

References:

St-Onge M, Anseeuw K, Cantrell FL et al, Experts Consensus Recommendations for the Management of Calcium Channel Blocker Poisoning in Adults. Crit Care Med. 2017 Mar;45(3):e306-e315.

2023 American Heart Association Focused Update on the Management of Patients With Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

Levine M, Curry SC, Padilla-Jones A, Ruha AM. Critical care management of verapamil and diltiazem overdose with a focus on vasopressors: a 25-year experience at a single center. Ann Emerg Med. 2013 Sep;62(3):252-8. doi: 10.1016/j.annemergmed.2013.03.018.

Cole JB, Arens AM, Laes JR, Klein LR, Bangh SA, Olives TD. High dose insulin for beta-blocker and calcium channel-blocker poisoning. Am J Emerg Med. 2018 Oct;36(10):1817-1824. doi: 10.1016/j.ajem.2018.02.004. Epub 2018 Feb 6.

Slamowitz A, Sweberg T, Labgold K, Nickerson T. Extracorporeal Membrane Oxygenation for Calcium Channel Blocker Intoxication: A Multicenter Retrospective Registry Review. ASAIO J. 2025 Oct 31.

Poison Control: (800) 222-1222

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